Junior Scientist – Peptide binding assays

About the role

Peptide therapeutics are one of the modalities we're building out at PopVax, and turning a designed peptide into a credible drug candidate depends on knowing, clearly and quantitatively, what it does to cells. Does it bind its target? Does that binding actually trigger the signaling cascade we expect?

What you'll do

• The work sits across mammalian cell culture, receptor-ligand interaction studies, the design and execution of signal transduction assays
• Maintaining and culturing mammalian cell lines as the workhorse of the assay platform
• Running expression experiments by performing transient transfections and, as programs require, generating stable cell lines
• Designing and running experiments that characterise how our peptides bind their targets and what that binding does
• Designing, optimising, and executing cell-based assays that measure receptor activation and downstream signaling – phosphorylation, reporter activation

What you need

• 0–3 yrs of experience
• Biology
• Chemistry
• GMP
• Clinical research
• B.Tech or B.E. or M.Tech or M.Sc